Table 4

Sensitivity and stratified analyses of pooled odds ratio for case–control studies
Ulcerative colitis Crohn’s disease
Stratified analysis Meta-regression Stratified analysis Meta-regression
No. of studies No. of cases No. of controls Pooled OR (95%CI) Heterogeneity (p-value) Coef. P value No. of studies No. of cases No. of controls Pooled OR (95%CI) Heterogeneity (p-value) Coef. P value
Crude 7 1491 3153 1.06 (0.78, 1.45) .004 9 2028 1002618 1.26 (1.03, 1.53) .16
Time of exposure
Time of data collection 4 1013 2511 1.18 (0.78, 1.80) .006 -0.32 .42 2 474 1511 1.21 (0.58, 2.50) .18 0.060 .89
Childhood 3 478 642 0.87 (0.65, 1.17) .91 5 1028 999115 1.18 (0.82, 1.70) .052
0-6 years 4 832 998908 1.12 (0.71, 1.77) .026 0.16 .46
< 16 years 1 196 207 1.39 (0.74, 2.60) NA
Source of controls
Population 2 314 487 1.02 (0.66, 1.58) .16 0.035 .94 3 835 998893 1.40 (1.13, 1.73) .37 -0.23 .32
Clinic/Hospital 5 1177 2666 1.06 (0.70, 1.60) .003 6 1193 3725 1.09 (0.79, 1.51) .11

Soon et al.

Soon et al. BMC Gastroenterology 2012 12:51   doi:10.1186/1471-230X-12-51

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