Table 1

Characteristics of cohort studies for ulcerative colitis and Crohn’s disease studies
Study characteristics and demographics Study Quality Characteristics
Author (year) Country Study period Number of cases Incidence of UC (per 100,000) Methods of diagnosis defined Diagnosis based on recognized criteria Urban/rural defined Urban population >10,000 Time of exposure Multiple levels of exposure
Ulcerative Colitis
Mate-Jimerez 1994 [39] Spain 1981-88 111 3.16 Yes Yes Yes Yes At diagnosis No
Ekbom 1991 [40] Sweden 1965-83 2509 10.5 Yes Yes Yes No At diagnosis No
Linden 1971 [19] Finland 1967 223 4.76 No N/A No No At diagnosis No
Probert 1992 [32] UK 1972-80 192 5.33 Yes Yes Yes No At diagnosis Yes
Probert 1992 [32] UK 1981-89 211 7.29 Yes Yes Yes No At diagnosis Yes
Niv 1990 [33] Israel 1967-86 43 2.33 Yes No Yes No At diagnosis Yes
Kildebo 1990 [22] Norway 1983-86 179 13.2 Yes Yes No No At diagnosis No
Gheorghe 2004 [23] Romania 2002-03 163 0.97 Yes Yes No No At diagnosis No
Sincic 2006 [41] Croatia 2000-04 70 4.6 Yes Yes Yes No At diagnosis No
Tsianos 1994 [24] Greece 1982-91 61 4.18 Yes Yes No No At diagnosis Yes
Ladas 2005 [34] Greece 1990-94 56 10.6 Yes Yes Yes Yes At diagnosis Yes
Moller 1971 [20] Finland 1956-67 505 1.07 Yes Yes No No At diagnosis No
Blanchard 2001 [42] Canada 1987-96 1763 15.6 Yes Yes Yes No At diagnosis No
Green 2006 [15] Canada 1990-01 N/A 13.5 No N/A Yes No At diagnosis No
Lakatos 2003 [43] Hungary 1977-01 560 5.89 Yes Yes Yes No At diagnosis No
Manousos 1996 [44] Greece 1990-94 117 8.9 Yes Yes Yes No At diagnosis No
Wigley 1962 [35] New Zealand N/A 132 N/A Yes No Yes Yes At diagnosis Yes
Latour 1996 [45] Belgium 1993-94 36 3.5 Yes Yes Yes No At diagnosis No
Crohn’s Disease
Kyle 1971 [47] UK 1955-69 166 1.98 Yes Yes Yes No At diagnosis No
Jayanthi 1992 [48] UK 1972-80 161 2.89 Yes Yes Yes Yes At diagnosis No
Jayanthi 1992 [48] UK 1981-89 233 4.48 Yes Yes Yes Yes At diagnosis No
Mate-Jimerez 1994 [39] Spain 1981-88 57 1.61 Yes Yes Yes Yes At diagnosis No
Ekbom 1991 [40] Sweden 1965-83 1469 6.09 Yes Yes Yes No At diagnosis No
Shivananda 1987 [36] Netherlands 1979-83 54 3.90 Yes Yes Yes No At diagnosis Yes
Kildebo 1989 [22] Norway 1983-86 82 5.85 Yes Yes No No At diagnosis No
Kyle 1992 [49] Scotland 1955-88 856 5.65 Yes Yes Yes No At diagnosis No
Manousos 1996 [44] Greece 1990-94 37 3.00 Yes Yes Yes Yes At diagnosis No
Gheorghe 2004 [23] Romania 2002-03 85 0.51 Yes Yes No No At diagnosis No
Sincic 2006 [41] Croatia 2000-04 100 6.50 Yes Yes Yes No At diagnosis No
Phavichitr 2003 [25] Australia 1971-01 351 1.02 Yes Yes No No At diagnosis No
Moum 1996 [50] Norway 1990-93 225 5.86 Yes Yes Yes No At diagnosis No
Blanchard 2001 [42] Canada 1987-96 1765 15.6 Yes Yes Yes No At diagnosis No
Green 2006 [15] Canada 1990-01 N/A 14.8 No N/A Yes No At diagnosis No
Lakatos 2003 [43] Hungary 1977-01 212 2.23 Yes Yes Yes No At diagnosis No
Nyhlin 1986 [51] Sweden 1974-81 253 4.90 Yes Yes Yes No At diagnosis No
Ruiz Ochoa 1984 [30] Spain 1976-83 152 0.80 Yes Yes No No At diagnosis No
Sedlack 1980 [31] USA 1935-75 103 4.20 Yes No No No At diagnosis No
Brandes 1983 [52] Germany 1964-75 97 3.00 Yes No Yes No At diagnosis No
Latour 1996 [45] Belgium 1993-94 56 5.50 Yes Yes Yes No At diagnosis No

Soon et al.

Soon et al. BMC Gastroenterology 2012 12:51   doi:10.1186/1471-230X-12-51

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