Table 1

Comparisons in socio-demographic status, co-morbidity and medication between esophageal cancer cases and controls frequency matched by sex, age and index year
Esophageal cancer
No Yes
N=2196 N=549
n % n % P value
Age, mean (SD), years 60.9 (3.03) 60.9 (12.9) 0.24
20-39 56 2.55 14 2.55 1.00
40-64 1,328 60.5 332 60.5
≥65 812 37.0 203 37.0
Sex 1.00
Women 156 7.10 39 7.10
Men 2,040 92.9 510 92.9
Comorbidity
Diabetes mellitus 222 10.1 57 10.4 0.85
Alcoholism 16 0.73 53 9.65 <0.0001
Obesity 4 0.18 1 0.18 1.00
Tobacco use disorder 7 0.32 5 0.91 0.07
Periodontal disease 33 1.50 2 0.36 0.03
HPV infection -- -- -- -- --
Hyperlipidemia 324 14.8 65 11.8 0.08
Barrett's esophagus -- -- -- -- --
Esophageal ulcer 18 0.82 50 9.11 <0.0001
Esophageal reflux 39 1.78 43 7.83 <0.0001
Medication
Use of aspirin 305 13.9 83 15.1 0.46
Use of COX-2 inhibitors 495 22.5 159 29.0 0.002
Use of other NSAIDs 1,877 85.5 522 95.1 <0.0001

Data are presented as the number of subjects in each group, with percentages given in parentheses.

Chi-square test and Fisher’s exact test comparing patients with and without esophageal cancer.

Cheng et al.

Cheng et al. BMC Gastroenterology 2012 12:177   doi:10.1186/1471-230X-12-177

Open Data