Table 5

Incidence rates and relative risks of gallbladder surgery (as-treated analysis)
Variable Events Person years Incidence rate1 95% Confidence interval Rate ratio1 95% Confidence interval
Low High Low High
Tegaserod Use
 Current 17 545 0.03 0.02 0.05 0.99 0.56 1.77
 Recent 10 179 0.06 0.03 0.10 1.78 0.88 3.59
 Past 10 401 0.02 0.01 0.05 0.85 0.42 1.72
 Non-Use 36 1,115 0.03 0.02 0.04 1.00
Gender
 Female 67 1,999 0.03 0.03 0.04 1.00
 Male 6 242 0.02 0.01 0.05 0.68 0.29 1.57
Age
 0 - 29 9 293 0.03 0.01 0.06 1.00
 30 - 49 44 1,135 0.04 0.03 0.05 1.35 0.66 2.77
 50 + 20 813 0.02 0.02 0.04 0.87 0.39 1.91
Gallbladder Surgery Risk Factors
 Cholelithiasis (574) 14 44 0.32 0.18 0.54 8.51 4.23 17.14
 Gallbladder or Bile Duct Surgeries 3 30 0.10 0.02 0.29 0.20 0.06 0.73
 Constipation (564.0) 17 814 0.02 0.01 0.03 0.56 0.32 0.96
 Diagnostic Procedures2 35 295 0.12 0.08 0.17 4.44 2.67 7.39

1 Adjusted for gender, age, cholelithiasis, gallbladder surgery, constipation, and diagnostic procedures.

2 Composite variable consisting of abdominal ultrasound and radiographic visualization of the gallbladder.

Seeger et al.

Seeger et al. BMC Gastroenterology 2012 12:171   doi:10.1186/1471-230X-12-171

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