Table 4

Incidence rates and relative risks of abdominal or pelvic surgery (as-treated analysis)
Variable Events Person years I.R.1 95% Confidence interval Rate ratio1 95% Confidence Interval
Low High Low High
Tegaserod Use
 Current 43 542 0.08 0.06 0.11 0.68 0.48 0.95
 Recent 25 177 0.14 0.09 0.21 1.17 0.76 1.80
 Past 28 393 0.07 0.05 0.10 0.59 0.39 0.89
 Non-Use 132 1,090 0.12 0.10 0.14 1.00
Gender
 Female 207 1,963 0.11 0.09 0.12 1.00
 Male 21 237 0.09 0.05 0.14 0.85 0.54 1.33
Age
 0 - 29 25 289 0.09 0.06 0.13 1.00
 30 - 49 144 1,110 0.13 0.11 0.15 1.47 0.96 2.26
 50 + 59 802 0.07 0.06 0.09 0.85 0.53 1.36
Surgery Risk Factors
 Cholelithiasis (574) 19 43 0.45 0.27 0.69 3.25 2.00 5.28
 Colonoscopy (45355–45387) 54 496 0.11 0.08 0.14 0.95 0.69 1.31
 Irritable Bowel Syndrome (564.1) 89 910 0.10 0.08 0.12 0.88 0.67 1.15
 Gastritis and Duodenitis (535) 47 312 0.15 0.11 0.20 1.37 0.98 1.91
 Diagnostic Procedures2 80 437 0.18 0.15 0.23 1.92 1.45 2.55

1 Adjusted for gender, age, cholelithiasis, colonoscopy, irritable bowel syndrome, gastritis and duodenitis, and diagnostic procedures.

2 Composite variable consisting of MRI abdomen, other diagnostic procedures involving the abdomen or pelvis, radiologic small bowel examination, rectum or anus diagnostic procedures, urinary tract diagnostic procedures, radiographic visualization of the gallbladder, and abdominal radiologic examination.

Seeger et al.

Seeger et al. BMC Gastroenterology 2012 12:171   doi:10.1186/1471-230X-12-171

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