Table 2 |
|||
The diagnostic performance of liver SWV and FibroTest in classifying METAVIR fibrosis (F) stages | |||
METAVIR | |||
F1vsF2-4 | F1-2vsF3-4 | F1-3vsF4 | |
Liver SWV | |||
AUC (95% CI) | 0.847(0.779-0.914) | 0.902 (0.835-0.970) | 0.831 (0.723-0.939) |
SE of AUC | 0.034 | 0.035 | 0.055 |
Cutoff (m/s) | 1.55 | 1.81 | 1.98 |
Sensitivity | 74.1% | 90.2% | 88.9% |
Specificity | 87.0% | 89.5% | 79.8% |
PPV | 90.9% | 80.4% | 42.1% |
NPV | 65.6% | 95.0% | 97.8% |
Concordance | 78.8% | 89.7% | 81.1% |
Discordance | 21.2% | 10.3% | 18.9% |
+LR | 5.7 | 8.6 | 4.4 |
-LR | 0.3 | 0.1 | 0.1 |
DOR(95% CI) | 19.0(7.1-51.3) | 79.1(22.9-273.8) | 31.6(6.8-147.9) |
FibroTest | |||
AUC (95% CI) | 0.823(0.748-0.898) | 0.812 (0.735-0.888) | 0.757 (0.648-0.865) |
SE of AUC | 0.038 | 0.039 | 0.055 |
Concordance = (true positive n + true negative n)/127, and discordance = (false positive n + false negative n)/127; AUC, area under the receiver operating characteristic curve; DOR, diagnostic odds ratio; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; SE, standard error; SWV, shear wave velocity.
Chen et al.
Chen et al. BMC Gastroenterology 2012 12:105 doi:10.1186/1471-230X-12-105