Table 1

Patient characteristics
Variable METAVIR F0-3 METAVIR F4 Pvalue
n = 109 n = 18
Age, year 51.6(1.2) 62.7(1.5) <.001
Gender (n) 1.000
Male 51 8
Female 58 10
BMI, kg/m2 24.64(0.33) 24.02(0.79) .477
HCV genotype (n) 1.000
1 53 9
Non-1 56 9
HCV RNA, x 106, copies/mL 8.16(1.21) 1.02(0.52) <.001
ALT, IU/L 97.94(8.24) 64.28(8.07) .005
ALT/ULN (n) .273
<1x 26 5
≧1x <2x 35 7
≧2x <3x 21 5
≧3x <4x 7 1
≧4x 20 0
ActiTest, A score 0.51(0.03) 0.51(0.06) .928
Bilirubin, umol/L 16.80(0.54) 22.36(2.00) <.001
Cr, umol/L 71.80(4.34) 65.42(4.35) .301
INR 1.02(0.01) 1.12(0.03) <.001
Na, meq/L 137.90(0.24) 137.83(0.60) .918
Platelet, x 109/L 176.61(5.67) 121.44(9.73) <.001
Child-Pugh grade (n)
A 16
B 2
C
METAVIR F (n)
F0 0
F1 46
F2 40
F3 23
F4 18
METAVIR A (n) .484
A0 31 3
A1 60 10
A2 16 5
A3 2 0
Hepatic steatosis (n) 1.000
S0 15 2
S1 37 6
S2 52 10
S3 4 0
S4 1 0
Liver SWV, m/s 1.65(0.06) 2.62(0.19) <.001
FibroTest, F score 0.57(0.03) 0.79(0.04) <.001

Continuous variables were presented as mean (standard error) and examined using the Student’s t test. Categorical variables were estimated using Fisher’s exact test. ALT, serum alanine aminotransferase; Cr, serum creatinine; INR, international normalized ratio of prothrombin time; METAVIR A, activity; METAVIR F, fibrosis; Na, serum sodium; SWV, shear wave velocity.

Chen et al.

Chen et al. BMC Gastroenterology 2012 12:105   doi:10.1186/1471-230X-12-105

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