Table 1

Clinical features

Case

Gender

Age (y)

tTGAa

EMAb

Symptoms

Mal-absorption

Diagnostic clues for detecting celiac disease


1

M 52

> 100

1:2000

Subtle

Vitamin B12 deficiency

2

M 52

29.2

1:2000

None

-

Fracture of hand

3

F 52

> 100

1:4000

None

+

Pernicious anemia, hypothyroidism

4

F 52

8.2

1:50

None

+

Blisters in mouth, family history

5

F 52

35.7

1:500

Subtle

-

6

F 52

> 100

1:2000

Subtle

+

7

M 53

29.7

1:200

Subtle

-

Sarcoidosis, family history

8

M 53

6.1

1:5

Subtle

-

Family history

9

F 53

6.2

0

Subtle

+

Fracture of vertebra, osteomalacia hypothyroidism

10

M 54

88.3

1:1000

None

+

Fracture of ankle, psoriasis

11

M 54

93.0

1:500

None

+

12

F 55

> 100

1:500

Subtle

-

Sjögren's syndrome, psoriasis

13

F 55

43.4

1:500

None

-

Osteoporosis

14

M 55

24.5

1:200

Subtle

+

Psoriasis, osteoporosis

15

F 56

58.5

1:200

Classic

-

Family history

16

F 56

18.3

1:50

None

-

Family history

17

F 56

46.6

1:1000

None

-

Type I diabetes mellitus, hypothyroidism

18

M 62

97.4

1:500

None

+

Depression, vitamin B12 deficiency

19

F 63

5.8

1:5

None

+

20

M 63

38.9

1:1000

Subtle

+

Sarcoidosis, osteoporosis

21

F 63

94.1

1:200

None

-

Hypothyroidism

22

F 63

16.5

1:100

None

+

Hyperthyroidism, family history

23

F 64

71.2

1:500

None

+

Fracture of ribs and sternum, osteoporosis

24

M 64

5.8

1:5

None

+

Fracture of wrist

25

F 64

10.5

1:5

None

-

26

F 65

> 100

1:500

Subtle

+

Osteoporosis

27

F 65

64.3

1:200

Subtle

-

Hypothyroidism, family history

28

F 66

79.8

1:500

Subtle

+

Hypothyroidism, family history

29

M 72

> 100

1:200

Subtle

+

Fracture of foot, family history

30

M 73

27.4

1:50

Subtle

+

31

M 73

20.2

1:200

None

+

Fracture of ribs, osteoporosis blisters in mouth

32

M 75

6.0

1:5

None

+

Osteoporosis

33

F 76

7.4

1:5

None

-

Osteoporosis

34

M 76

5.4

1:5

None

+

Fracture of ribs, family history

35

F 76

48.3

1:500

None

-

Stomach cancer


Clinical features of screen-detected celiac disease patients having small bowel mucosal villous atrophy at the time of diagnosis.

A Serum IgA-class tissue transglutaminase antibodies, values > 5.0 U/l abnormal

B Serum IgA-class endomysial antibodies, titers 1:≥5 abnormal

C Sarcoidosis treated with immunosuppressive medication

Vilppula et al. BMC Gastroenterology 2011 11:136   doi:10.1186/1471-230X-11-136

Open Data