Table 3

Multivariate ordinal logistic regression analysis of risk factors associated with polyp size in males and females

Males (n = 48,395)

Females (n = 34,246)

OR

(95% CI)

OR

(95% CI)


Age

< 50

1.00

1.00

50 - 59

1.06

(0.98 - 1.16)

1.00

(0.91 - 1.11)

60 - 69

1.29

(1.18 - 1.40)**

1.14

(1.03 - 1.26)*

70 - 79

1.36

(1.24 - 1.49)**

1.34

(1.20 - 1.49)**

80+

1.55

(1.35 - 1.79)**

1.46

(1.25 - 1.70)**

Site

Academic

1.00

1.00

Community/HMO

1.26

(1.18 - 1.34)**

1.22

(1.13 - 1.33)**

VA/Military

0.97

(0.90 - 1.05)

0.90

(0.78 - 1.03)

Race

White

1.00

1.00

Black

1.31

(1.21 - 1.42)**

1.36

(1.24 - 1.48)**

Location

Distal Colon and rectum

1.00

1.00

Proximal Colon

1.11

(1.08-1.15)**

1.33

(1.27-1.39)**

Number of polyps

Single

1.00

1.00

Multiple

3.41

(3.29 - 3.54)**

3.04

(2.90 - 3.18)**

Family history

Negative

1.00

1.00

Positive

1.00

(0.95 - 1.05)

1.03

(0.98 - 1.08)


All odds ratios are adjusted for all other covariates in the table. * P < .01 **P < .0001

Odds Ratios (OR) and 95% Confidence Intervals (CI) obtained from ordinal logistic regression. Polyp size was stratified into 4 categories: 0-5, > 5-9, > 9-15, and > 15-40 mm. The odds ratio is the risk associated with an increase of polyp size corresponding to moving from one category to the next larger category, i.e. ≤ 5 mm vs. > 5 mm; ≤ 9 vs. > 9; ≤ 15 vs. > 15 mm.

Lowenfels et al. BMC Gastroenterology 2011 11:101   doi:10.1186/1471-230X-11-101

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