Increase in liver mass following CCl4 treatment. For both genotypes liver mass (presented as the percent of body weight for each mouse, bar represents the median value) increased after CCl4 injury as expected. The difference was statistically significant at both Day 3 and Day 5 for the WT mice (vs. WT vehicle, * P = 0.05, ** P = 0.01). Liver mass increases in a similar fashion for GC-C KO mice up to Day 3 (GC-C KO vehicle vs. Day 3, * P = 0.05) but is not significantly different by Day 5.
Mann et al. BMC Gastroenterology 2010 10:86 doi:10.1186/1471-230X-10-86