Figure 4.

Staining of IBAT protein in the Ileal Mucosal Brush Border from Wild-Type, Heterozygous and Cystic Fibrosis Mice. An increase in IBAT protein staining intensity was observed in microscopic sections of the terminal ileum of knock-out mice. IBAT signal intensities were higher in heterozygous knock-out mice and still higher in homozygous mutants compared to wild-type controls. Jejunal mucosa showed no IBAT signals.