Table 1

Overview of the test characteristics of the four selection methods.

6 cl. method 3%FA1
 6 cl. method 10%FA2
 4 cl. method 3%FA3
 4 cl. method 10%FA4

women
 men
 women
 men
 women
 men
 women
 men
Sensitivity
 94,2
 89,4
 94,0
 93.1
 89.4
 93.6
 94.7
 91.5
Specificity
 99,8
 99,8
 99,3
 99.8
 99.8
 99.6
 99.6
 99.1
PPV5
 93,7
 93,7
 94,3
 98.2
 93.7
 89.5
 96.3
 93.1
NPV6
 99,8
 99,6
 99,2
 99.0
 99.6
 99.8
 99.3
 98.8
Kappa
 0.937
 0.912
 0.934
 0.950
 0.912
 0.911
 0.949
 0.912










3 cl. method 3%FA7
 3 cl. method 10%FA8
 3 group method 3%FA9
 3 group method 10%FA10

women
 men
 women
 men
 women
 men
 women
 men
Sensitivity
 89.0
 84.8
 96.0
 85.5
 76.1
 73.6
 79.3
 86.5
Specificity
 99.3
 99.3
 98.3
 98.8
 99.1
 99.4
 98.5
 97.6
PPV
 88.1
 80.4
 87.8
 90.6
 74.1
 82.3
 86.9
 83.1
NPV
 99.6
 99.5
 99.5
 98.0
 99.2
 99.1
 97.4
 98.1
Kappa
 0.881
 0.819
 0.906
 0.864
 0.742
 0.770
 0.809
 0.826










6 cl. method
 4 cl. method
 3 cl. method
 3 group method

3% FA
 10% FA
 3% FA
 10% FA
 3% FA
 10% FA
 3% FA
 10% FA

Men and women
 Men and Women
 Men and women
 Men and Women
Sensitivity
 91.8
 93.5
 90.9
 93.0
 86.9
 90.6
 74.8
 83.0
Specificity
 99.8
 99.5
 99.7
 99.3
 99.4
 98.5
 99.3
 98.0
PPV
 93.7
 96.3
 91.4
 94.6
 84.1
 89.1
 78.0
 84.8
NPV
 99.7
 99.1
 99.7
 99.1
 99.5
 98.7
 99.1
 97.7
Kappa
 0.925
 0.942
 0.912
 0.930
 0.849
 0.885
 0.756
 0.818

1. 6 cl. method: selection FAs per 10 years of age.

2. Idem

3. 4 cl. method: selection of FAs per 15 years of age

4. Idem

5. positive predictive value

6. negative predictive value

7. 3 cl. method: selection of FAs in 3 age groups (15–44; 45–64; 65–74).

8. Idem

9. 3 group method: selection of male FAs in two age groups (15–44; 45–74) and women in one group.

10. Idem

Smits et al. BMC Family Practice 2008 9:21   doi:10.1186/1471-2296-9-21