Table 3

Test accuracy of NT-proBNP and the clinical risk score for identifying left ventricular systolic dysfunction.*


True Positive
False Positive
False Negative
True Negative
Sensitivity (%)
Specificity (%)
Likelihood ratio of negative result (95% CI)

NT-proBNP (< 98.5 pg/ml)
21
282
2
237
91 (71 to 98)
46 (41 to 50)
0.19 (0.05 to 0.71)
Risk score (< 1.11)
21
189
2
330
91 (71 to 98)
64 (59 to 67)
0.14 (0.04 to 0.51)

*At cut-off points with comparable high sensitivity and moderate specificity in order to rule out left ventricular dysfunction in case of a negative result (SnNout; very high sensitivity: negative result rules out the diagnosis/disease. Values in parentheses are 95% confidence intervals.

Koschack et al. BMC Family Practice 2008 9:14   doi:10.1186/1471-2296-9-14