Table 2

Sensitivities (sens), specificities (spec), positive and negative predictive values (PPV and NPV), odds ratios (OR) and likelihood ratios (LR+ and LR-) of clinical signs and symptoms and C-reactive protein (CRP) for the presence of obstructive airway disease (n = 60)

Signs/Symptoms

Sens

95% CI

Spec

95% CI

PPV

95% CI

NPV

95% CI

OR

95% CI

LR +

95% CI

LR -

95% CI


CRP > 2 mg/l

62.2

46.1–75.9

72.7

51.9–86.9

79.3

61.6–90.2

53.3

36.1–69.8

4.4

1.4–13.8

2.3

1.1–4.7

0.5

0.3–0.8

Dyspnea

62.2

46.1–75.9

47.8

29.2–67.0

65.7

49.2–79.2

44.0

26.7–62.9

1.5

0.5–4.3

1.2

0.8–1.9

0.8

0.4–1.4

Coughing

29.7

17.5–45.8

34.8

18.8–55.1

42.3

25.5–61.1

23.5

12.4–40.0

0.2

0.1–0.7

0.5

0.3–0.8

2.0

1.1–3.7

Expectoration

40.5

26.3–56.5

69.7

49.1–84.4

68.2

47.3–83.6

42.1

27.9–57.8

1.6

0.5–4.7

1.3

0.6–2.8

0.9

0.6–1.3

Wheezing

75.7

59.9–86.6

52.2

33.0–70.8

71.8

56.2–83.5

57.1

36.5–75.5

3.4

1.1–10.3

1.6

1.0–2.5

0.5

0.2–0.9

Smoking history

62.2

46.1–75.9

52.2

29.2–67.0

65.7

49.2–79.2

44.0

26.7–62.9

0.7

0.2–1.9

1.2

0.8–1.9

0.8

0.4–1.4

Auscultation

27.8

15.8–44.0

87.0

67.9–95.5

76.9

49.7–91.8

43.5

30.2–57.8

2.6

0.6–10.6

2.1

0.7–6.9

0.8

0.6–1.1


Schneider et al. BMC Family Practice 2006 7:28   doi:10.1186/1471-2296-7-28

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