Table 3

Immunoglobulin Secretion from B-cells after in-vitro mitogenic stimuli in Pediatric Hypogammaglobulinemia

SAC

PWM

LPS

IgM

IgG

IgA

IgM

IgG

IgA

IgM

IgG

IgA

Hypogamma

1.6

1.2 *

1.1 **

1.1 *

1.4 *

1.3 *

1.3 *

2.0 *

1.1 *

(0.6–2.6)

(0.9–1.5)

(1.0–1.2)

(0.9–1.3)

(0.9–1.9)

(1.0–1.6)

(1.1–1.5)

(1.1–2.9)

(1.0–1.2)

Corrected

2.8

1.0 *

1.3 *

1.0 *

1.1 **

1.3 *

2.2 *

1.5 *

1.2 *

(1.7–3.9)

(0.9–1.1)

(1.0–1.6)

(0.9–1.1)

(1.0–1.2)

(1.1–1.5)

(1.4–3.0)

(1.2–1.8)

(1.0–1.4)

Normal

3.0

2.5

2.3

2.6

3.0

2.2

4.4

5.0

3.4

(2.5–3.5)

(1.9–3.1)

(1.8–2.8)

(2.2–3.0)

(2.4–3.6)

(1.7–2.7)

(3.9–4.9)

(3.5–6.5)

(3.0–3.8)

SAC – Staph. Aureus Cowan. PWM – Pokeweed Mitogen

LPS – Lipopolysacharide

Values are given as Secretion Index Mean and (95% confidence interval)

** p < 0.005 compared to normal controls

* p < 0.05 compared to normal controls

Kidon et al. BMC Family Practice 2004 5:23   doi:10.1186/1471-2296-5-23