Table 1 

Comparison of MetaAnalysis Software 

Stata/WinBUGS 
R/OpenBUGS 
MIX 
CMA 
RevMan 
MetaAnalyst 



Operating system 
Windows, Mac, Linux 
Windows, Mac, Linux 
Windows 
Windows 
Windows, Mac, Linux 
Windows 


Version 
10 
2.6 
1.7 
2 
5.0.18 
Beta 1.0 


Price 
$785* 
FREE 
FREE 
$1,295 
FREE 
FREE 


Import data 
✓ 
✓ 
✓ 
✓ 
✓ 



Metaanalysis interface/routines 
Macros 
Macros 
Dedicated 
Dedicated 
Dedicated 
Dedicated 


Metaregression 
✓ 
✓ 
∅ 
✓ 
∅ 
✓ 


Single group 
✓ 
✓ 
✓^{†} 
✓ 
✓^{†} 
✓ 


Fixed effects 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Random effects 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Multilevel models 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Random effects metaregression 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Bayesian models 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Cumulative metaanalysis 
✓ 
✓ 
✓ 
✓ 
∅ 
✓ 


Subgroup analysis 
✓ 
✓ 
∅ 
✓ 
✓ 
✓ 


Small study effects (Publication bias tests)** 
✓ 
✓ 
✓ 
✓ 
∅ 
∅ 


Binary data 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Continuous data 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Diagnostic test data 
✓ 
✓ 
∅ 
∅ 
✓ 
✓ 


Multivariate 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Documentation of methods 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Forest plot 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


Funnel plot 
✓ 
✓ 
✓ 
✓ 
✓ 
✓ 


SROC 
✓ 
✓ 
∅ 
∅ 
✓ 
✓ 


HSROC  bivariate metaanalysis 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Point and click plot editing 
✓ 
∅ 
∅ 
∅ 
∅ 
✓ 


Programming capabilities 
✓ 
✓ 
∅ 
∅ 
∅ 
✓ 


Leave one out sensitivity 
✓ 
✓ 
∅ 
✓ 
∅ 
✓ 


Results format 
RTF 
RTF 
MS Excel 
RTF, PowerPoint 
RevMan 
PDF, RTF, image files 


* Intercooled Stata for a single processor, educational licence. Other versions are more expensive. ^{† }One group analysis available for continuous outcomes only. **Recent empirical research challenges the routine use of the socalled "publication bias diagnostics" [1921]. RTF: Rich text format (can be opened in MS Word); SROC: summary receiver operating characteristic curve 

Wallace et al. BMC Medical Research Methodology 2009 9:80 doi:10.1186/14712288980 