BMC Medical Research Methodology

official impact factor 2.15

Open Access Research article

Estimating the number needed to treat from continuous outcomes in randomised controlled trials: methodological challenges and worked example using data from the UK Back Pain Exercise and Manipulation (BEAM) trial

Robert Froud1*, Sandra Eldridge1, Ranjit Lall2 and Martin Underwood2

Author Affiliations

1 Centre for Health Sciences, Barts and the London School of Medicine and Dentistry, London, E1 2AT, UK

2 Warwick Clinical Trials Unit, Warwick Medical School, Gibbet Hill Road, Coventry, CV4 7AL, UK

For all author emails, please log on.

BMC Medical Research Methodology 2009, 9:35 doi:10.1186/1471-2288-9-35

Published: 11 June 2009

Additional files

Additional file 1:

Supplement. A word document detailing equations for both of the methods described. Stata modules to perform these tasks are available from the corresponding author on request.

Format: DOC Size: 192KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data