Table 3

Ranges for interpretation of I2 following the Cochrane Handbook for Systematic Reviews of Interventions (Version 5.0.1) [23].

0% to 40%

might not be important

30% to 60%

may represent moderate heterogeneity

50% to 90%

may represent substantial heterogeneity

75% to 100%

considerable heterogeneity


Rücker et al. BMC Medical Research Methodology 2008 8:79   doi:10.1186/1471-2288-8-79

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