|
Reporting characteristics for the analysis of interacting environmental factors for randomly selected HuGE articles (2001–2003) |
||
| Reporting characteristic |
Count* |
Percent |
|
|
||
| Number of environmental factors assessed in gene-environment interactions |
||
| 1 |
34 |
70.8 |
| 2 |
10 |
20.8 |
| >= 3 |
4 |
8.4 |
| Potential for misclassification of the environmental factors |
||
| No |
7 |
14.6 |
| Unclear |
4 |
8.3 |
| Yes |
37 |
77.1 |
| Provided a description of possible error in the measurement of the environmental factor |
||
| No |
45 |
93.8 |
| Yes |
3 |
6.2 |
| Use of dose-depending models |
||
| No |
45 |
93.8 |
| Yes |
3 |
6.2 |
| Reported that the evaluation of the genetic test was blind to the environmental factor |
||
| Blind |
0 |
0.0 |
| Unclear |
48 |
100.0 |
| Reported that the evaluation of the environmental factor was blind to the genetic test |
||
| Blind |
0 |
0.0 |
| Unclear |
48 |
100.0 |
| If gene-environmental interactions were assessed, was risk quantified as an odds ratio or risk ratio |
||
| No |
22 |
45.8 |
| Yes |
26 |
54.2 |
| If gene-environmental interactions were assessed, was risk quantified as an absolute difference |
||
| No |
48 |
100.0 |
| Yes |
0 |
0.0 |
| If gene-environmental interactions were assessed, was risk quantified as an attributable fraction |
||
| No |
48 |
100.0 |
| Yes |
0 |
0.0 |
| Claim of a statistically significant gene-environmental interaction |
||
| No |
34 |
70.8 |
| Yes |
14 |
29.2 |
|
* limited to the 48 studies that addressed at least 1 environmental factor | ||
Yesupriya et al. BMC Medical Research Methodology 2008 8:31 doi:10.1186/1471-2288-8-31 |
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