|
Microarray Gene Expression data results (n = 2009 genes, m = 3 replicates) |
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| (a) Technical replicate |
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|
|
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| Affymetrix (l = 1) |
Amersham (l = 2) |
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| Estimate |
SE |
Estimate |
SE |
|
|
|
||||
| μl |
2759 |
150.5 |
3.74 |
0.22 |
| ρ l |
0.94 |
0.002 |
0.99 |
0.0003 |
| θl |
0.58 |
0.03 |
0.25 |
0.015 |
| σl |
1603 |
17.88 |
0.93 |
0.01 |
| ρ12 = 0.51, Twald = 11.85, LRT = 122, PM = -7.89 (p < 0.001 for all tests) The estimate of the common WSCV under the null is 0.31 (SE = 0.014) 95% CI for (θ1-θ2): (0.28, 0.39) |
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|
|
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| (b) Biological replicate |
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|
|
||||
| Affymetrix (l = 1) |
Amersham (l = 2) |
|||
| Estimate |
SE |
Estimate |
SE |
|
|
|
||||
| μl |
2819 |
142.6 |
3.43 |
0.18 |
| ρ l |
0.91 |
0.003 |
0.93 |
0.0025 |
| θl |
0.71 |
0.037 |
0.63 |
0.034 |
| σl |
2003.7 |
22.35 |
2.16 |
0.02 |
| ρ12 = 0.50, Twald = 2.35, LRT= 8.56, PM = -9.04 (p < 0.02 for all tests) The estimate of the common WSCV under the null is 0.67 (SE = 0.025) 95% CI for (θ1-θ2): (0.014, 0.15) |
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Shoukri et al. BMC Medical Research Methodology 2008 8:24 doi:10.1186/1471-2288-8-24 |
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