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Breakdown of retrieved trials by Therapeutic Area |
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| Therapeutic Area |
Total number of trials retrieved in search |
Trials reporting interim analysis (with or without specification of a DMC) |
Trials identified as having extended use of interim data or DMC recommendations with the potential to introduce bias |
|
|
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| Total (N) |
1772 |
586 |
28 |
| Cardiovascular Disease (CVD) |
494 |
209 |
11 |
| Oncology (ONC) |
387 |
136 |
11 |
| Infection (INF) |
271 |
93 |
2 |
| Pediatrics (PED) |
71 |
22 |
0 |
| Obstetrics & Gynecology (OBGYN) |
43 |
20 |
2 |
| Neurology (NEURO) |
50 |
17 |
1 |
| Other |
456 |
89 |
1 |
Tharmanathan et al. BMC Medical Research Methodology 2008 8:12 doi:10.1186/1471-2288-8-12 |
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