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Open AccessResearch article

The fallacy of enrolling only high-risk subjects in cancer prevention trials: Is there a "free lunch"?

Stuart G Baker1 email, Barnett S Kramer2 email and Donald Corle1 email

1Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA

2Office of Disease Prevention, National Institutes of Health, Bethesda, Maryland, USA

author email corresponding author email

BMC Medical Research Methodology 2004, 4:24doi:10.1186/1471-2288-4-24

Published: 4 October 2004

Additional files

Additional File 1:

Appendix A, worked-out calculations of power.

Format: PDF Size: 67KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 2:

Appendix B, likelihood formulations

Format: PDF Size: 74KB Download file

This file can be viewed with: Adobe Acrobat Reader


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