Table 1

Hypothetical data for a binary marker from a nested case-control study

Marker -

Marker +

Total


No cancer

990

10

1000

Cancer

20

80

100


True positive rate (TPR) = 80/100 = .80 = sensitivity False positive rate (FPR) = 10/1000 = .01 = 1 – specificity

Baker et al. BMC Medical Research Methodology 2002 2:4   doi:10.1186/1471-2288-2-4

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