Table 2

Results of meta-analyses of trials of high intensity nursing to reduce smoking using standard§ and 'treat-as-one-trial' methods, with relative risk as effect measure

Setting (no. of trials)

Number quitting/total

Pooled risk ratio (95% CI)

NNT (95% CI)


Intervention

Control


Hospital (7)

435/1367

318/1295

Meta-analysis

1.30 (1.16 to 1.47)

13.6 (8.7 to 25.5)¶¶

Treat-as-one-trial

1.30 (1.15 to 1.47)

13.8 (9.4 to 25.9)

Primary Care (3)*

111/2453

41/1006

Meta-analysis

1.01 (0.71 to 1.42)

2454 (58.4 to H84.6)¶¶

Treat-as-one-trial

1.11 (0.78 to 1.58)

222.5 (52.0 to H97.7)

Primary Care (2)**

87/2246

25/958

Meta-analysis

1.54 (0.97 to 2.44)

71.0 (26.6 to H1277)¶¶

Treat-as-one-trial

1.48 (0.96 to 2.30)

79.1(39.2 to H4369)


§ Mantel-Haenszel method (fixed effect) * as defined by Moore et al ** excluding reference [12] NNT for harm [13]¶¶NNT calculated using the event rate among controls and the relative risk reduction [4]

Altman and Deeks BMC Medical Research Methodology 2002 2:3   doi:10.1186/1471-2288-2-3

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