Table 2 |
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Results of meta-analyses of trials of high intensity nursing to reduce smoking using standard§ and 'treat-as-one-trial' methods, with relative risk as effect measure |
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|
Setting (no. of trials) |
Number quitting/total |
Pooled risk ratio (95% CI) |
NNT (95% CI) |
|
|
|
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|
Intervention |
Control |
|||
|
|
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|
Hospital (7) |
435/1367 |
318/1295 |
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|
Meta-analysis |
1.30 (1.16 to 1.47) |
13.6 (8.7 to 25.5)¶¶ |
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|
Treat-as-one-trial |
1.30 (1.15 to 1.47) |
13.8 (9.4 to 25.9) |
||
|
Primary Care (3)* |
111/2453 |
41/1006 |
||
|
Meta-analysis |
1.01 (0.71 to 1.42) |
2454 (58.4 to H84.6¶)¶¶ |
||
|
Treat-as-one-trial |
1.11 (0.78 to 1.58) |
222.5 (52.0 to H97.7¶) |
||
|
Primary Care (2)** |
87/2246 |
25/958 |
||
|
Meta-analysis |
1.54 (0.97 to 2.44) |
71.0 (26.6 to H1277¶)¶¶ |
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|
Treat-as-one-trial |
1.48 (0.96 to 2.30) |
79.1(39.2 to H4369¶) |
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|
|
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§ Mantel-Haenszel method (fixed effect) * as defined by Moore et al ** excluding reference [12]¶ NNT for harm [13]¶¶NNT calculated using the event rate among controls and the relative risk reduction [4] |
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Altman and Deeks BMC Medical Research Methodology 2002 2:3 doi:10.1186/1471-2288-2-3 |
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