Table 4

Association of Fetal Hypoxia at Birth1 and Diagnosis of Autism Spectrum Disorders2: Results of Logistic Regression Fitted with EM Algorithm for Handling Unknown Exposures That are Modeled From Maternal and Birth Characteristics Under Specific NMAR Assumption Among Full-Term Male Births

Deviation from MAR3

Strong

Strong

Moderate

Weak


r

0.1

0.2

0.5

0.7


Odds ratio estimate

1.28

1.28

1.24

1.20


95% confidence interval

1.03, 1.60

1.03, 1.58

1.01, 1.52

0.99, 1.46


P-value

0.03

0.03

0.04

0.06


1: at least one of the three tests for fetal hypoxia is positive, i.e. fetal scalp pH < 7.25, or umbilical artery pH < 7.20, or venous pH < 7.28

2: singletons born in Alberta 1998-2004 and followed up till March 31, 2008, effects adjusted for birth year and socio-economic status

3: contribution of clinical judgment to prescribing the test beyond Z; MAR = missing at random, r = 1, see Table 3

Burstyn et al. BMC Medical Research Methodology 2011 11:2   doi:10.1186/1471-2288-11-2

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