Table 2 |
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|
Adjustment for Differences in Patient Characteristics between Study Arms: Sensitivity to Prior Distributions |
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|
Type of Prior |
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|
Dataset |
Posterior Estimate Median OR (95% credible interval) |
Base Case Analysis: " Reasonably Vague" (Grines) |
Sensitivity Analysis: "Fairly Unrestrictive" (Prevost) |
Sensitivity Analysis: " Vaguest" |
|
|
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|
Overall (μ) |
0.37 (0.17,0.77) |
0.37 (0.23,0.60) |
0.37 (0.18,1.25) |
|
|
Base Case 3 Covariatesa (k = 44) |
Randomised (θ1) |
0.35 (0.17,0.63) |
0.36 (0.21,0.59) |
0.34 (0.13,0.74) |
|
Non-Randomised (θ2) |
0.39 (0.25,0.61) |
0.38 (0.25,0.57) |
0.40 (0.23,0.68) |
|
|
Overall (μ) |
0.45 (0.20,0.95) |
0.47 (0.28,0.74) |
0.44 (0.13,1.31) |
|
|
Imputed 5 Covariatesb (k = 79) |
Randomised (θ1) |
0.42 (0.18,0.78) |
0.46 (0.25,0.73) |
0.39 (0.14,0.87) |
|
Non-Randomised (θ2) |
0.49 (0.33,0.72) |
0.49 (0.33,0.71) |
0.49 (0.32,0.74) |
|
|
|
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|
a.male, age, cardiac disease, b.male, age, cardiac disease, pulmonary disease, renal disease |
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|
McCarron et al. BMC Medical Research Methodology 2010 10:64 doi:10.1186/1471-2288-10-64 |
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