Table 1

Characteristics of practice guidelines: reporting of conflicts of interest.

Conflicts of interest

Conflicts of interest

Exact

reported

not reported

p-value

N = 7

N = 184


Journal

NEJM

0

7

0.026

JAMA

4

31

Lancet

0

9

Annals

2

31

BMJ

1

17

Pediatrics

0

89

Year

1979

0

22

<0.001

1984

0

40

1989

0

47

1994

0

42

1999

7

33

Disclosure policy

Yes

7

108

0.043

No

0

76

Focus

Therapy

1

59

0.14

Prevention

3

100

Both

3

25

Main country

Europe

1

25

1.00

America

6

159

Group Authorship

Yes

6

155

1.00

No

1

29

Drug Intervention*

Yes

2

50

1.00

No

5

134

Funding

Government

1

39

<0.001

Private

2

9

University

0

35

Other†

1

98

Mixed†

3

3

Authors ‡

1-2

1

30

0.004

3-9

2

22

10-17

3

2


P-values are based on Fisher's exact test. * emphasis placed on medications rather than on vaccines, devices, surgical interventions, nutritional interventions, counseling, screening, rehabilitation and other non-pharmaceutical interventions † other sources of funding include mostly professional organizations (American College of Physicians, American Academy of Pediatrics, American Medical Association); mixed source of funding is defined as a combination of two or more of the four categories of funding ‡ n=60 for this analysis; 30 guidelines did not have group authorship and another 30 guidelines specified specific individuals who were primarily responsible for writing the manuscript, even if group authorship was mentioned

Papanikolaou et al. BMC Medical Research Methodology 2001 1:3   doi:10.1186/1471-2288-1-3

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