Table 3

Likelihood ratios for the diagnosis of ACS with clinical myocardial infarction at presentation


Positive likelihood ratio (95% CI)
Negative likelihood ratio (95% CI)

Serial ECG & ST monitoring N = 690
7.1 (3.8 to 13.1)
0.700 (0.543 to 0.901)
Initial CK-MB(mass) N = 687
20.8 (12.5 to 34.7)
0.378 (0.236 to 0.605)
Delayed CK-MB(mass) N = 601
25.1 (16.5 to 38.2)
0.045 (0.007 to 0.307)
Delta CK-MB(mass) N = 601
61.4 (39.1 to 118.1)
0.044 (0.006 to 0.300)
Any positive CK-MB(mass) N = 601
~25*
~0*
Troponin T > = 0.1 ng/ml N = 686
70.4 (34.1 to 140.8)
0.169 (0.079 to 0.387)
Troponin T > = 0.03 ng/ml N = 686
23.5 (16.1 to 34.2)
0.037 (0.005 to 0.255)

*Unable to calculate precisely as no false negative were recorded

Goodacre et al. BMC Emergency Medicine 2005 5:6   doi:10.1186/1471-227X-5-6