Table 2

Sensitivity, specificity, positive and negative predictive values for the diagnosis of ACS with clinical myocardial infarction at presentation


Sensitivity (95% CI)
Specificity (95% CI)
Positive predictive value (95% CI)
Negative predictive value (95% CI)

Serial ECG & ST monitoring N = 690
33.3% (19.2 to 51.2)
95.3% (93.4 to 96.7)
24.4% (13.8 to 39.3)
96.9% (95.3 to 98.0)
Initial CK-MB(mass) N = 687
63.3% (45.5 to 78.1)
97.0% (95.3 to 98.0)
48.7% (33.9 to 63.8)
98.3% (97.0 to 99.0)
Delayed CK-MB(mass) N = 601
95.7% (79.0 to 99.2)
96.2% (94.3 to 97.5)
50.0% (35.8 to 64.2)
99.8% (99.0 to 100)
Delta CK-MB(mass) N = 601
95.7% (79.0 to 99.2)
98.4% (97.0 to 99.1)
70.0% (53.4 to 83.9)
99.8% (99.0 to 100)
Any positive CK-MB(mass) N = 601
100% (88.6 to 100)
95.6% (93.7 to 96.9)
50.8% (38.3 to 63.2)
100% (99.4 to 100)
Troponin T > = 0.1 ng/ml N = 686
83.3% (66.4 to 92.7)
98.8% (97.7 to 99.4)
75.8% (59.0 to 87.2)
99.3% (98.3 to 99.7)
Troponin T > = 0.03 ng/ml N = 686
96.4% (82.3 to 99.4)
95.9% (94.1 to 97.2)
50.0% (37.1 to 62.9)
99.8% (99.1 to 100)

Goodacre et al. BMC Emergency Medicine 2005 5:6   doi:10.1186/1471-227X-5-6