Table 2

Sensitivity, specificity, positive and negative predictive values for the diagnosis of ACS with clinical myocardial infarction at presentation

Sensitivity (95% CI)

Specificity (95% CI)

Positive predictive value (95% CI)

Negative predictive value (95% CI)


Serial ECG & ST monitoring N = 690

33.3% (19.2 to 51.2)

95.3% (93.4 to 96.7)

24.4% (13.8 to 39.3)

96.9% (95.3 to 98.0)

Initial CK-MB(mass) N = 687

63.3% (45.5 to 78.1)

97.0% (95.3 to 98.0)

48.7% (33.9 to 63.8)

98.3% (97.0 to 99.0)

Delayed CK-MB(mass) N = 601

95.7% (79.0 to 99.2)

96.2% (94.3 to 97.5)

50.0% (35.8 to 64.2)

99.8% (99.0 to 100)

Delta CK-MB(mass) N = 601

95.7% (79.0 to 99.2)

98.4% (97.0 to 99.1)

70.0% (53.4 to 83.9)

99.8% (99.0 to 100)

Any positive CK-MB(mass) N = 601

100% (88.6 to 100)

95.6% (93.7 to 96.9)

50.8% (38.3 to 63.2)

100% (99.4 to 100)

Troponin T > = 0.1 ng/ml N = 686

83.3% (66.4 to 92.7)

98.8% (97.7 to 99.4)

75.8% (59.0 to 87.2)

99.3% (98.3 to 99.7)

Troponin T > = 0.03 ng/ml N = 686

96.4% (82.3 to 99.4)

95.9% (94.1 to 97.2)

50.0% (37.1 to 62.9)

99.8% (99.1 to 100)


Goodacre et al. BMC Emergency Medicine 2005 5:6   doi:10.1186/1471-227X-5-6

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