Table 3

Effect of various methods of handling missing response in trial
Methods of analysis PIH in TXA and placebo group
Group n/N Rate RD RR
(person) (%) [95% CI] [95% CI]
1. Complete case analysis TXA 16/115 14% −0.11 0.57
Placebo 28/114 25% [(−0.21)-(−0.01)] [0.32-0.99]
2. Assuming poor outcome TXA 21/120 18% −0.10 0.65
Placebo 32/118 27% [(−0.20)-(−0.01)] [0.40-1.05]
3. Assuming good outcome TXA 16/120 13% −0.10 0.56
Placebo 28/118 24% [(−0.20)-(−0.01)] [0.32-0.98]
4. Extreme case favoring placebo TXA 21/120 18% −0.06 0.74
Placebo 28/118 24% [(−0.16)-0.04] [0.44-1.22]
5. Extreme case favoring TXA TXA 16/120 13% −0.14 0.49
Placebo 32/118 27% [(−0.24)-(−0.04)] [0.29-0.85]

Yutthakasemsunt et al.

Yutthakasemsunt et al. BMC Emergency Medicine 2013 13:20   doi:10.1186/1471-227X-13-20

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