Table 3

Blood results at baseline and follow-up

Baseline

Post-treatment

Adjusted mean treatment difference

p-value

Placebo (n = 79)

Vitamins (n = 83)

Placebo (n = 79)

Vitamins (n = 83)


tHcy μmol/L

11.7 (10.9, 12.6)

10.3 (9.6, 11.1)

11.8 (10.9, 12.8)

7.9 (7.5, 8.4)

-3.7 ± 0.8

< 0.001

Serum B6 nmol/L

40 (36, 45)

34 (31, 38)

34 30, 38)

118 (116, 121)

79 ± 3

< 0.001

Serum B12 pmol/L

297 (266, 331)

317 (285, 351)

274 (248, 302)

638 (600, 680)

328 ± 25

< 0.001

RBC folate nmol/L

805 (732, 885)

884 (796, 982)

944 (839, 1061)

2534 (2401, 2673)

1475 ± 103

< 0.001

Cholesterol mmol/L

4.7 (4.5, 4.9)

4.8 (4.6, 5.0)

4.3 (4.2, 4.5)

4.4 (4.2, 4.6)

-0.1 ± 0.2

0.63

Triglycerides mmol/L

1.4 (1.2, 1.5)

1.5 (1.3, 1.6)

1.3 (1.1, 1.4)

1.3 (1.1, 1.4)

-0.1 ± 0.1

0.53

LDL* mmol/L

-

-

2.3 (2.1, 2.4)

2.3 (2.1, 2.4)

-

-

HDL mmol/L

-

-

1.3 (1.2, 1.4)

1.3 (1.2, 1.3)

-

-

Creatinine μmol/L

80 (76, 83)

79 (74, 84)

84 (81, 88)

88 (83, 90)

3.1 ± 3.0

0.30

Cystatin C mg/L

1.02 (0.97, 1.07)

1.05 (1.00, 1.11)

1.04 (0.99, 1.09)

1.08 (1.02, 1.15)

0.01 ± 0.03

0.69

GGT mmol/L

-

-

26 (22, 30)

30 (27, 34)

-

-

Glucose mmol/L

5.4 (5.3, 5.6)

5.5 (5.3, 5.7)

5.1 (4.9, 5.2)

5.2 (5.0, 5.4)

0.1 ± 0.2

0.59

HbA1c %

-

-

5.8 (5.6, 6.0)

5.9 (5.7, 6.1)

-

-


RBC indicates red blood cell; LDL, low density lipoprotein; HDL, high density lipoprotein; GGT, gamma glutamyl transpeptidase; HBA1c, glycated haemoglobin.

Baseline and follow-up values are presented as geometric mean (95% confidence interval)

Adjusted mean treatment differences are presented as mean ± standard error

P-values for the adjusted mean treatment differences are from a univariate general linear model.

* Calculated using the Friedewald equation

Potter et al. BMC Cardiovascular Disorders 2008 8:24   doi:10.1186/1471-2261-8-24

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