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Plasma total cholesterol (TC), triglycerides (TG), VLDL-C, LDL-C and HDL-C of guinea pigs fed a control diet, low dose MTPi (LDI), high dose MTPi (HDI) or atorvastatin |
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| Diets |
TC |
TG |
VLDL-C |
LDL-C |
HDL-C |
|
|
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| (mg/dL) |
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| Control (10) |
146.9 ± 42.2a |
135.8 ± 118.9a |
8.1 ± 5.5ab |
123.9 ± 43.5a |
13.6 ± 4.5a |
| LDI (10) |
116.9 ± 29.7b |
66.7 ± 29.6b |
3.7 ± 3.0a |
93.3 ± 26.2b |
18.5 ± 8.0a |
| HDI (9) |
116.1 ± 23.3b |
74.3 ± 31.7b |
9.0 ± 8.6b |
90.5 ± 28.8b |
15.6 ± 7.1a |
| Atorvastatin (9) |
76.5 ± 29.8c |
49.4 ± 32.2c |
2.9 ± 2.6a |
59.4 ± 29.3c |
14.1 ± 5.6a |
|
1Data are presented as mean ± SD for the number of guinea pigs indicated in parenthesis. Numbers in a column with different superscripts are considered significantly different (P < 0.01) as determined by one way ANOVA and LSD as a post-hoc test | |||||
Aggarwal et al. BMC Cardiovascular Disorders 2005 5:30 doi:10.1186/1471-2261-5-30 |
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