|
Composition of Control, low dose of the inhibitor (LDI), high dose of the inhibitor (HDI) and atorvastatin diets |
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| Components |
Control % |
LDI % |
HDI % |
Atorvastatin % |
|
|
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| Soybean protein |
22.5 |
22.5 |
22.5 |
22.5 |
| Methionine |
0.5 |
0.5 |
0.5 |
0.5 |
| Sucrose |
25 |
25 |
25 |
25 |
| Corn Starch |
15 |
15 |
15 |
15 |
| Fat mix1 |
15.1 |
15.1 |
15.1 |
15.1 |
| Cellulose |
10 |
10 |
10 |
10 |
| Guar gum |
2.5 |
2.5 |
2.5 |
2.5 |
| Mineral Mix2 |
8.2 |
8.2 |
8.2 |
8.2 |
| Vitamin Mix2 |
1.1 |
1.1 |
1.1 |
1.1 |
| Cholesterol |
0.08 |
0.08 |
0.08 |
0.08 |
| JTT-130 |
0 |
0.0005 |
0.0015 |
0 |
| Statin |
0 |
0 |
0 |
0.05 |
|
1 Fat mix for the diet contains olive oil-palm kernel oil-safflower oil (1:2:1.8), high in lauric and myristic acids. 2 Mineral and vitamin mix adjusted to meet NRC requirements for guinea pigs. Detailed composition of the vitamin and mineral mix has been reported elsewhere (Fernandez et al. 1992b). | ||||
Aggarwal et al. BMC Cardiovascular Disorders 2005 5:30 doi:10.1186/1471-2261-5-30 |
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