Table 5

Sensitivity analysis of adjusted odds ratio and 95% confidence interval for new AMI hospitalization and NSAIDs use on different definition of case and control period

days before index date

Case period

Control period

1-30

91-120

8-30

98-120

1-30

61-90

aOR*

95%CI

aOR*

95%CI

aOR*

95%CI




ns-NSAIDs

Oral overall

1.42

1.29 - 1.56

1.19

1.08 - 1.31

1.48

1.35 - 1.63

Parental overall

3.35

2.50 - 4.47

1.85

1.34 - 2.57

2.81

2.13 - 3.70

Oral

celecoxib

1.42

0.99 - 2.04

1.19

0.83 - 1.71

1.03

0.73 - 1.46

ketorolac

2.02

1.00 - 4.09

2.58

1.25 - 5.33

2.37

1.23 - 4.59

diclofenac

1.29

1.13 - 1.47

1.13

0.99 - 1.30

1.46

1.28 - 1.66

Parenteral

ketorolac

4.27

2.90 - 6.29

1.98

1.25 - 3.13

2.90

2.05 - 4.10

ketoprofen

2.34

1.31 - 4.19

1.77

0.97 - 3.22

1.98

1.12 - 3.50

diclofenac

1.88

0.95 - 3.75

1.14

0.53 - 2.47

2.35

1.09 - 5.08


aOR = adjusted odds ratio; 95%CI = 95% confidence interval; ns-NSAIDs = non-selective NSAIDs

* Conditional logistic regression adjusted for time-varying confounding variables of discordant use of antihypertensive agents, angiotensin converting enzyme inhibitors or aldosterone receptor blockers, calcium channel blockers, statins, insulin, sulfonylurea, thiazolidinedione, and aspirin between case and control period.

Shau et al. BMC Cardiovascular Disorders 2012 12:4   doi:10.1186/1471-2261-12-4

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