Table 2

Characteristics of the study sample of patients stratified according to the eGFR
Normal eGFR (group 1) Mild decreased eGFR (group 2) Moderate decreased eGFR (group 3) P Values
ANOVA or χ2 group 1 vs group 2 group 1 vs group 3 group 2 vs group 3
Age (years) 56 ± 11.5 63,0 ± 11.7 70.0 ± 9.4 <0.001 0.001 <0.001 0.05
Gender (male/female) 31/17 76/43 20/13 0.928
Family history of hypertension (yes/no) 25/23 69/50 19/14 0.778
Family history of stroke (yes/no) 11/37 22/97 6/27 0.790
Smokers (yes/ex/no) 13/8/27 8/27/7 27/75/21 0.379
Diabetes (yes/no) 5/43 11/108 4/29 0.883
Diastolic BP (mmHg) 73.2 ± 14.0 77.3 ± 11.5 73.0 ± 9.8 0.048 0.129 1 0.185
Systolic BP (mmHg) 124.5 ± 23.3 137.5 ± 20.0 130.2 ± 27.3 0.002 0.002 0.754 0.286
Pulse pressure (mmHg) 51.3 ± 14.1 60.1 ± 16.9 57.3 ± 23.3 0.014 0.010 0.396 1
Fasting blood glucose (mmHg) 99.7 ± 32.2 102.8 ± 20.0 106.7 ± 23.9 0.432 1 0.589 1
Total Cholesterol (mg/dl) 178.9 ± 36.4 187.7 ± 40.8 189.0 ± 45.8 0.395 0.610 0.817 1
BMI (kg/m2) 27.4 ± 5.2 28.1 ± 4.6 26.7 ± 3.5 0.261 1 1 0.379
Beta-blockers (yes/no) 15/33 41/78 11/22 0.924
Alphabeta-blockers (yes/no) 5/43 14/105 2/31 0.639
Alpha-blockers (yes/no) 3/45 8/111 5/28 0.252
Diuretics (yes/no) 17/31 49/70 21/12 0.03
ACE inhibitor (yes/no) 16/32 48/71 11/22 0.604
Dihydropyridine (yes/no) 12/36 30/89 10/23 0.826
eGFR (mL/min/1.73 m2) 101.9 ± 12.0 74.3 ± 8.8 50.6 ± 8.0 <0.001 <0.001 <0.001 <0.001
IMT (mm) 1.8 ± 0.76 2.23 ± 1.21 2.91 ± 2.85 0.007 0.282 0.005 0.81
Vascular abnormalities (no/ thickening/plaque) 33/6/9 91/13/15 28/3/2 0.502
LVMi g/m2 124.3 ± 26. 2 133.0 ± 32.3 130.4 ± 32.1 0.258 0.301 1 1
Left Ventricular hypertrophy (no/yes) 24/24 44/75 12/21 0.268

Data are expressed as mean and standard deviation for continuous variables (i.e. age) and as number of patients per each group for categorical variables (i.e. gender).

The p-values refer to ANOVA and post-hoc comparisons with Bonferroni corrections for continuous variables, to χ2 for categorical variables.

Melillo et al.

Melillo et al. BMC Cardiovascular Disorders 2012 12:105   doi:10.1186/1471-2261-12-105

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