Figure 1.

Effect of spironolactone on echocardiographic left ventricular function in sham, myocardial infarct (MI) and MI+spironolactone rats. (A) left ventricular fractional shorting (LV FS), (B) LV fractional area change (LV FAC), (C) Right ventricular myocardial performance index (RV MPI) and (D) Right ventricular tricuspid annulus plane systolic excursion (RV TAPSE). Results are expressed as mean±SEM. *p < 0.0001 vs. Sham; †p < 0.05 vs. Sham.