Research article
Novel Toll-like receptor-4 deficiency attenuates trastuzumab (Herceptin) induced cardiac injury in mice
BMC Cardiovascular Disorders 2011, 11:62 doi:10.1186/1471-2261-11-62
intersting study!!
MARIA LUISE
(2011-11-17 13:53) MD,ANDERSON CANCER CENTER 
This is agood study to explained the mechanism of trastuzumab toxicity.
Competing interests
None declared
use in the clinical
Joon Anderson (2011-11-17 13:57) Research Institute
This is a good study, but we need to confirm this result in the clinical trial, because the cardiomyopathy is a real adverse effect of trastuzumab when we used it in the treatmnet of Her2/neu positive breast cancer.
Anderson
Competing interests
None declared
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