Table 6

Non-parametric comparisons of cardiac parameters after 4 weeks of exposure to isoproterenol and treatment with P188 in BL10 and mdx mice.

Measurement

Group

N

Median

Range

Overall p-value

Significantly different groups


Heart rate (bpm)

BL10 - Untx

3

450

421 - 476


BL10 - Iso

7

615

532 - 656


MDX - Untx

6

438

400 - 489

0.0004

BL10-Iso vs. MDX-Untx (p = 0.0267)


MDX - Iso

9

585

541 - 667

MDX-Untx vs. MDX-Iso (p = 0.0149)


MDX - Iso + P188

5

632

615 - 667


Bpm - beats per minute; iso - isoproterenol; untx - untreated

Spurney et al. BMC Cardiovascular Disorders 2011 11:20   doi:10.1186/1471-2261-11-20

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