Table 1

Propylene glycol specimens showing confluent degenerative changes on histology
PG concentration Perineural inflammation Confluent changes
Axon degeneration Myelin degeneration Intraneural inflammation
n (%) n (%) n (%) n (%)
0% n=9 5 (56%) possible in 3 (33%) 0 (0%) 0 (0%) 0 (0%)
2.5% n=8 8 (100%) 0 (0%) 0 (0%) 0 (0%)
10% n=8 8 (100%) 0 (0%) 0 (0%) 0 (0%)
35% n=8 8 (100%) 0 (0%) * 0 (0%) * 2 (25%) *
70% n=9 9 (100%) 5 (56%) 5 (56%) 6 (66%)

PG: Propylene glycol.

* Two specimens showed patchy axonal and myelin degeneration with intraneural inflammation in smaller fascicles, rather than confluent changes.

Belavy et al.

Belavy et al. BMC Anesthesiology 2013 13:18   doi:10.1186/1471-2253-13-18

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