Table 2

Haemodynamic variables and microcirculatory parameters for all measurements as well as per CVP group
All (n = 140) CVP ≤12 mmHg (n = 80) CVP >12 mmHg (n = 60) P a
MAP (mmHg) 70 ± 13 68 ± 12 75 ± 13 0.443
Cardiac index (l/min/m2) 4.2 ± 1.3 4.3 ± 1.1 4.0 ± 1.5 0.121
CVP (mmHg) 12.3 ± 4.6 9.0 ± 2.8 16.6 ± 2.4 0.000*
Perfusion pressure (mmHg) 57 ± 13 55 ± 13 59 ± 12 0.055
PEEP (cm H2O) 13 ± 3 13 ± 3 14 ± 3 0.053
SvO2 (%) 71 ± 7.9 72 ± 7.0 68 ± 8.5 0.003*
Lactate (mmol/L) 2.6 ± 2.2 1.8 ± 1.4 3.6 ± 2.6 0.000*
Dopamine (n,%, μg/kg/min) 121, 86, 6.7 ± 3.1 66, 83, 5.9 ± 2.7 55, 92, 7.9 ± 3.1 0.000*,b
Norepinephrine (n,%, μg/kg/min) 68, 49, 0.14 ± 0.15 32, 40, 0.10 ± 0.06 36, 60, 0.18 ± 0.19 0.013*,b
MFI (AU) 1.70 ± 0.95 1.89 ± 0.91 1.44 ± 0.94 0.006*
PPV (%) 92 ± 15 95 ± 8 88 ± 21 0.006*
TVD (mm/mm2) 14.18 ± 2.11 14.31 ± 1.95 14.00 ± 2.31 0.410
PVD (mm/mm2) 13.70 ± 7.88 14.66 ± 9.81 12.42 ± 3.8 0.066

Mean ± SD unless specified otherwise. CVP = Central venous pressure. MAP = mean arterial pressure. Perfusion pressure = MAP minus CVP. SvO2 = mixed venous oxygen saturation. MFI = microvascular flow index. AU = arbitrary units. TVD = total vessel density. PPV = percentage of perfused vessels. PVD = perfused vessel density. TVD, MFI, PPV and PVD for small vessels, i.e. < 20 μmeter. *P < 0.05 is considered statistically significant. a For differences between CVP-groups. bfor difference in dose between CVP groups.

Vellinga et al.

Vellinga et al. BMC Anesthesiology 2013 13:17   doi:10.1186/1471-2253-13-17

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