Table 2

Time to recovery of the train-of-four ratio to 0.9, 0.8, and 0.7.

Sugammadex (n = 47)

Neostigmine (n = 36)


Time to TOF ratio of 0.9, min

Geometric mean

4.5*

66.2

Median

3.3

49.9

Interquartile range

2.3-6.6

46.0-96.6

Range

1.4-68.4

46.0-312.7

Time to TOF ratio of 0.8, min

Geometric mean

3.3*

58.9

Median

2.7

43.9

Interquartile range

1.8-4.4

42.9-79.8

Range

1.2-65.2

35.3-250.9

Time to TOF ratio of 0.7, min

Geometric mean

2.6*

48.8

Median

2.5

36.4

Interquartile range

1.6-3.3

34.9-67.5

Range

1.1-61.9

27.5-192.2


Recovery times were measured from the start of administration of sugammadex or neostigmine. Data are given for the intent-to-treat population, with imputed data.

*p < 0.0001 versus neostigmine. Data include the patient who received rocuronium plus neostigmine reversal rather than vecuronium plus sugammadex reversal in error, the times to a TOF ratio of 0.9 and 0.8 were not available. Her times to TOF 0.9 and 0.8 were imputed based on her time to TOF 0.7 of 61.9 minutes.TOF, train-of-four.

Lemmens et al. BMC Anesthesiology 2010 10:15   doi:10.1186/1471-2253-10-15

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