Additional file 5.
Figure S3. Model of the domestication of a hAT transposase by a retrocopy process. This figure is based on a figure by Vaknin et al. . An active hAT transposase gene is transcribed into mRNA. A promiscuous reverse-transcriptase reverse-transcribes the spliced mRNA into cDNA, which subsequently becomes inserted in the genome. This process results in a retrocopy that is devoid of any introns and regulatory sequences. Promoter and UTR sequences can be obtained by the retrocopy from its neighboring sequences, or by a nearby secondary integration event of another transposable element. Acquisition of UTR’s or coding material is a process called exonisation and can eventually yield a functional and actively transcribed gene: a retrogene. Overlapping ellipses represent hAT transposon associated host duplications and the adjacent arrows represent terminal inverted repeats. UTR’s are depicted as light grey boxes, coding sequences as dark grey boxes and promoter boxes as white boxes. Exons are indicated with lines. Start of transcription is marked by an arrow.
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Knip et al. BMC Plant Biology 2012 12:192 doi:10.1186/1471-2229-12-192