Figure 4.

Domain organization of the KMT2 class proteins. Schematic diagrams show the domain organization of KMT2 proteins and are placed on the right side of the phylogenetic tree. The scale bar indicates the evolutionary distance, the number along the tree branch indicates bootstrap value, and the other information about tree construction and symbol indication can be found in legend of Figure 1. Different conserved protein domains (PWWP, FYR, GYF, PHD, SET, and Post-SET) are colored as indicated. The protein is indicated on top of the schematic diagram and other similar domain organization proteins are indicated in parentheses.