Figure 6.

Proportion of high and medium molecular weight adiponectin in KKA^y mice. Velocity sedimentation analysis of serum from KKA^y mice treated with the indicated amounts of compound BVT116429 or vehicle was performed. This is a representative immunoblot showing the changes of the different adiponectin forms. Several independent analyses were performed giving similar results. The two main adiponectin complexes, HMW and MMW bands, are indicated by arrows and molecular mass markers are shown.