Figure 5.

Inhibition or enhancement of the TPA-induced activation of AP-1 by analogs of trans-stilbenes. Screening with the 293/AP-1-luc cell of a range of analogs of stilbenes that retain the trans double bond demonstrated that inhibitors or enhancers of the TPA-induced activation of AP-1 can deviate considerably from the trans-stilbene scaffold. The * notation indicates p < 0.01.