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Open AccessHighly AccessResearch article

Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds

John C Boik email and Robert A Newman email

Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, 8000 El Rio, Houston, TX 77054, USA

author email corresponding author email

BMC Pharmacology 2008, 8:12doi:10.1186/1471-2210-8-12

Published: 13 June 2008

Additional files

Additional File 1:

Supplemental Tables. Three additional tables that summarize data sets and results.

Format: DOC Size: 35KB Download file

This file can be viewed with: Microsoft Word Viewer

Additional File 2:

Oral clearance and bioavailability values. A table of oral clearance and bioavailability values used in the manuscript.

Format: PDF Size: 144KB Download file

This file can be viewed with: Adobe Acrobat Reader

Additional File 3:

A short mathematical explanation of the KMLA algorithm. A short mathematical explanation of the KMLA algorithm.

Format: DOC Size: 295KB Download file

This file can be viewed with: Microsoft Word Viewer


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