Table 2

Correlation of SH-SY5Y cell α2-AR pKi values with those of native and cloned α2-AR subtypes.
Comparison
 Reference
 # of Values Compared
 Correlation Coefficient
 Slope
 p value
v. HT29
 21,22
 6
 0.93
 1.48 ± 0.41
 0.07
v. NG108-15
 21
 6
 0.13
 0.17 ± 0.91
 0.87
v. OK
 21,22
 6
 0.62
 0.99 ± 0.73
 0.27
v. α2C10
 23
 6
 0.80
 1.04 ± 0.45
 0.10
v. α2C2
 23
 6
 0.40
 0.48 ± 0.65
 0.50
v. α2C4
 23
 6
 0.70
 0.94 ± 0.52
 0.16
v. BE(2)-C
 6
 6
 0.98*
 1.38 ± 0.18
 0.01

Correlation coefficient values (r) were generated by comparing pKi values from Table 1 with previously published values for one-site models using Pearson correlation analysis (GraphPad Prism). The slope of the linear regression line is also included. Correlations were considered significant (*) if p ≤ 0.05.

Bawa-Khalfe et al. BMC Pharmacology 2007 7:16   doi:10.1186/1471-2210-7-16