Figure 3.

Fluorescence kinetics of Ce6-PVP on NSCLC (▲) and SCLC (■) xenografted on CAM examined up to 24 h post topical drug administration. Values are expressed as red-to-blue intensity ratio of fluorescence images post administration of drug normalized with images before drug administration. For tumor, each point represents a mean of 5 eggs whereas for normal (●), each point represents a mean of 10 eggs. Bars = standard error of the mean. Non-linear regression analysis demonstrated that all the curves were statistically different with each other. The elimination rate constant for NSCLC, SCLC and normal CAM was in the following order: NSCLC < SCLC < normal CAM.