Figure 7.

Effect of SB220025 on JNK activation. Cells were stimulated with LPS and SB220025. Incubations were terminated after 1 h and parallel immunoblots were run from same cell lysates using antibodies against Thr183/Tyr185 phosphorylated JNK (pp54 and pp46), total JNK (p54 and p46). Phosphorylated JNK values were normalised to total JNK values. The result is representative of three experiments with similar results.