Figure 3.

Heterologous competition binding curves of LE404 (■) and LE410 (●) at hD₁ (A), hD_2L (B), and 5HT_2A (C) receptors. Data shown are the means ± SEM of specific binding of at least four determinations assayed in triplicate. A. 0.2 nM [³H]SCH23390 was used for hD₁ receptors. Nonspecific binding was determined with 1 μM LE300. B. 0.1 nM [³H]spiperone was used for hD_2L receptors. Nonspecific binding was determined with 1 μM haloperidol. C. 0.1 nM [³H]spiperone was used for h5HT_2A receptors. Nonspecific binding was determined with 1 μM ketanserin.